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Scientific Studies

Psychological Support, Puberty Suppression, and Psychosocial Functioning in Adolescents with Gender Dysphoria
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A study found that both psychological support and puberty blockers improved mental health for transgender youth.


Puberty Blockers: A Review of GnRH Analogues in Transgender Youth
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A review of research on puberty blockers for transgender youth. It finds they are helpful with minor risks.


Psychological Functioning in Transgender Adolescents Before and After Gender-Affirmative Care Compared With Cisgender General Population Peers
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A study found that puberty blockers decreased emotional and behavioral problems compaired to transgender youth who did not get treatment and a cisgender control group.


Longitudinal impact of gender-affirming endocrine intervention on the mental health and well-being of transgender youths: preliminary results
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A study shows that transgender youth who get treatment have better mental health.


Body Dissatisfaction and Mental Health Outcomes of Youth on Gender-Affirming Hormone Therapy
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A study found that transgender youth who got gender affirming horomone therapy had less body dissatisfaction and somewhat better mental health.


Gender identity and transition: relationships with sleep disorders in US youth
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A study found that transgender youth have more sleep disorders and that having gender affirming care is linked with less of them.


Continuation of gender-affirming hormones in transgender people starting puberty suppression in adolescence: a cohort study in the Netherlands>
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A study of 720 transgender youth in the Netherlands found that 98% of people continued treatment into adulthood. This shows regret rates from gender-afferming care are likely quite low.


Hormonal therapy and sex reassignment: a systematic review and meta-analysis of quality of life and psychosocial outcomes
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A review of 28 studies found that most transgender people had less gender dyphoria and better mental health after HRT and surgry that was around the population baseline.


Long-term follow-up: psychosocial outcome of Belgian transsexuals after sex reassignment surgery
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A long term follow up study found that gender reassignment surgery redused attepted suicide rates from around 30% to around 5%


Suicidality among trans people in Ontario: Implications for social work and social justice
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A study found that transition decreased attepted suicide rates in the past year from 27% to 1%. It also found that social support helped.


Biased Science: The Texas and Alabama Measures Criminalizing Medical Treatment for Transgender Children and Adolescents Rely on Inaccurate and Misleading Scientific Claims
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A report finds the data used to backup the Texas and Alabama anti transgender health care laws were not rooted in science. The report finds Texas AG opinion and the Alabama Law have many scientific errors and make many omissions of data.


A Critical Review of the June 2022 Florida Medicaid Report on the Medical Treatment of Gender Dysphoria
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A report finds the data used to backup the Flordia's anti transgender health care limitations were not rooted in science. It finds Flordia's report had many errors and issues.


What does the scholarly research say about the well-being of children with gay or lesbian parents?
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A analysis of 79 studies that studied same sex parenting. 75 of those studies found no negative affect while the other 4 were found to have methodological issues.


The Effects of Marriage, Civil Union, and Domestic Partnership Laws on the Health and Well-being of Children
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A study that reviewers the literature around same sex parenting found no negative affect on children


Efficacy and safety of medical treatment in the clinical management of adolescents with gender dysphoria (gd): a prospective follow-up study
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A relatively small study characterized some health effects of gender affirming treatments on transgender youth and found they helped mental health.


Lesbian, Gay, Bisexual and Transgender (LGBT) Parented Families A Literature Review prepared for The Australian Psychological Society
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A study that reviewed the literature around same sex parenting found no negative affect on children


Difference-in-Differences Analysis of the Association Between State Same-Sex Marriage Policies and Adolescent Suicide Attempts
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A study found that states with same sex marriage policies had lower suicide rates among sexual orientation minority youth.


Effects of Medical Interventions on Gender Dysphoria and Body Image: A Follow-Up Study
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A study found access to gender afferming horomones and surgery was linked to better body image. It also found sugery combined with horomones lead to less gender dyphoria.


Hormonal Therapy Is Associated With Better Self-esteem, Mood, and Quality of Life in Transsexuals
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A study found gender afferming horomoes is linked to better self esteem, mood and quality of life.


Measuring Sex, Gender Identity, and Sexual Orientation
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A report on measuring LGBT+ identity that gives recommendations on how to collect LGBT+ data in the medical world.


Gender Identity 5 Years After Social Transition
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A study found that the detransition rate of transgender kids who social transition is 2.5% after 5 years.


Is Hormonal Therapy Associated with Better Quality of Life in Transsexuals? A Cross‐Sectional Study
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A study found gender afferming horomoes is linked to much better quality of life.


The Effects of Hormonal Gender Affirmation Treatment on Mental Health in Female-to-Male Transsexuals
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A study found FtM transgender people who got gender afferming horomones had less depression and anxiety. More social support was also linked to better mental health.


Suicide risk in the UK trans population and the role of gender transition in decreasing suicidal ideation and suicide attempt
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A study found social and medical transition lowered suicidal thoughts in a sample of more than 800 people. It also found medical delays and social stigma increased suicide rate.


What does the scholarly research say about the effect of gender transition on transgender well-being?
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A meta anaylsis of 55 studies on gender transition found that gender transition improves the mental health of transgender people. 51 of the 55 studies shows positive results while 4 of the 55 studies were inconclusive.


Issues Impacting LGBTQ Youth
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A survey by The Trevor Project looked at issues affecting LGBT+ youth and the effect of these issues on mental health. The survey found that unsurprisingly anti LGBT+ hate and anti transgender laws had a large effect on mental health.


Do Clinical Data from Transgender Adolescents Support the Phenomenon of “Rapid Onset Gender Dysphoria”?
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A study criticizing rapid onset gender dysphoria. It finds that a core claim of rapid onset gender dysphoria is not backed up by data.


The Trevor Project Research Brief: Gender-Affirming Care for Youth
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A overview of reasearch on medical and social transition for youth. It finds many studies that show both of these types of transition are helpful.


Association of Gender-Affirming Hormone Therapy With Depression, Thoughts of Suicide, and Attempted Suicide Among Transgender and Nonbinary Youth
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A study finds that access to gender affirming hormoens lead to lower levels of depression, thoughts of suicide, and attempted suicide in transgender youth. This is yet another study finding that medical transition for youth saves lives.


Humanistic and Economic Burden of Conversion Therapy Among LGBTQ Youths in the United States
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A study that reviews 28 other studies found LGBT+ conversion therapy is very bad for mental health and loses the US $9.23 billion a year.


What does the scholarly research say about whether conversion therapy can alter sexual orientation without causing harm?
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A analysis of 47 other studies finds that conversion therapy has a negitive effect and does not change sexual orientation.


Sexual Orientation Change Efforts, Adverse Childhood Experiences, and Suicide Ideation and Attempt Among Sexual Minority Adults, United States, 2016-2018
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A study found that sexual orientation change efforts increased attempted suicide rates by 75%.


Blanchard's Autogynephilia Theory: A Critique
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A critique of autogynephilia that finds many claims are not backed up by data and finds many other problems with the theory.


Mental Health Outcomes in Transgender and Nonbinary Youths Receiving Gender-Affirming Care
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Yet another study finds that gender affirming care such as purberty blockers and hormoens lowers sucicide risk. It found a 60% lower odds of depression and 73% lower odds of suicidality.


Transgender medicine - puberty suppression
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A overview on puberty blocker research that talks about rational for use of puberty blockers and shows they are mostly reversable without many large side effects.


Regret after Gender-affirmation Surgery: A Systematic Review and Meta-analysis of Prevalence
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A study that shows regret after getting gender affirmation surgery is less then 1%. This shows that detransition is not as big of a problem as TERFs put it out to be. Some of the regret actually came from people being non binary and not binary transgender or bad sugical outcomes showing that the regret from the transition itself is even lower.


Long-Term Follow-Up of Adults with Gender Identity Disorder
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A study found that transgender people who transitoned had much better mental health.


Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior
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A study found that there were many genes linked to people being homosexual. This is another piece of data showing being gay is not a choice.


Genetic Link Between Gender Dysphoria and Sex Hormone Signaling
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A study found there are multible genes linked to being transgender. This shows being transgender is not a choice and has deeper causes.


Puberty Suppression in Adolescents With Gender Identity Disorder: A Prospective Follow‐Up Study
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A study finds that transgender youth who get puberty blockers have better behavioral and emotional health while also having less depression symptoms.


Young adult psychological outcome after puberty suppression and gender reassignment
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A study found medical transition for transgender youth improved well-being and mental health.


Well-being and suicidality among transgender youth after gender-affirming hormones
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A study found that suicidality decreases and well-being increases when transgender youth get gender affirming hormones.


Pubertal Suppression for Transgender Youth and Risk of Suicidal Ideation
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A study found that puberty blockers were linked with a lower risk of suicidal thoughts.


Well-being and suicidality among transgender youth after gender-affirming hormones.
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A study found that gender afferming horomones lead to a significant decrease suicidality and a significant increase in well-being.


A Systematic Review of the Psychological Benefits of Gender-Affirming Surgery
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A review of studies found that gender afferming surgery has large psychological upsides.


National Survey on LGBTQ Youth Mental Health 2021
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A survey on LGBT+ youth mental health.


Methodological Critique of Littman’s (2018) Parental-Respondents Accounts of “Rapid-Onset Gender Dysphoria”
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A critique of the rapid onset gender dyphoria study that exposes its methodological flaws.


Abolishing legal sex status: The challenge and consequences of gender-related law reform
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A report on the ramifications of abolishing legal gender.


Sex Assigned at Birth Ratio Among Transgender and Gender Diverse Adolescents in the United States
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A study that finds a flaw with a claim of the Rapid Onset Gender Dysphoria theory.


A critical commentary on follow-up studies and “desistance” theories about transgender and gender-nonconforming children
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A commentary on several studies that looked at desistance among transgender kids find they likely overestimated desistance rates.


Individual Treatment Progress Predicts Satisfaction With Transition-Related Care for Youth With Gender Dysphoria: A Prospective Clinical Cohort Study
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A study found most transgender youth were satisfied with the care they got


Youth and Parent Experiences in a Multidisciplinary Gender Clinic
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A study found that most transgender youth and their parents were satisfied with the care they got


Patient and Parent Experiences of Care at a Pediatric Gender Service
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A study found that most transgender youth and their parents were satisfied with the care they got


Satisfaction With Male-to-Female Gender Reassignment Surgery
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A study found patients were satisfied with the results of gender affirming surgery and benefited from it


Factors Associated with Satisfaction or Regret Following Male-to-Female Sex Reassignment Surgery
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A study found that people who under sex realignment surgery were satisfied with the results and had a greater quality of life


Guiding the conversation—types of regret after gender-affirming surgery and their associated etiologies
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A study that surveyed surgeons who preformed gender affirming surgery found that their patents rarely regretted it


Sex reassignment: outcomes and predictors of treatment for adolescent and adult transsexuals
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A study found that gender affirming care was linked to better mental health and less dysphoria


Interrogating Gender-Exploratory Therapy
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An article that criticizes Gender-Exploratory Therapy (a new and non-affirming approach to dealing with transgender youth) and draws connections with it and conversion therapy